4SC AG: 4SC provides Q1 2022 update

Planegg-Martinsried (pta010/19.04.2022/07:30 UTC+2)

Planegg-Martinsried, Germany, 19 April 2022 – 4SC AG (4SC, FSE Prime Standard: VSC) today published the Q1 Announcement 2022, presenting all material developments up to 31 March 2022 and the Company's current outlook. The full communication is available for download on 4SC's website.

Jason Loveridge, Ph.D., CEO of 4SC, commented: "In February 2022 we decided to discontinue the domatinostat program and focus solely on resminostat and achieving an outcome to the pivotal RESMAIN study. These actions have helped us to preserve cash and provide sufficient runway to enable the company to execute on its revised plan until late in 2023. Progress on RESMAIN has been very positive in Q1 2022, with further patients recruited, bringing the total to 199. As a result, and as we now have achieved more than 90% of the events required to unblind RESMAIN, we now expect topline data earlier than previously expected – around the end of Q1 2023."

Development of cash balance in Q1 2022 and financial forecast

As of 31 March 2022, 4SC holds cash balance/funds of €25.018 million as compared to €29.022 million as of 31 December 2021. The monthly use of cash from operations amounted to €1.667 million on average in the first quarter of 2022 (Q1 2021: €1.538 million) and was within the range of €1.500 million and €1.800 million forecast for 2022.

Following the recent restructuring the Management Board of 4SC estimates that current funds should be sufficient to finance 4SC into Q4 2023.

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Further information

About 4SC

4SC AG is a clinical-stage biopharmaceutical company developing small-molecule drugs that target key indications in cancer with high unmet medical needs. 4SC's pipeline is protected by a comprehensive portfolio of patents and currently comprises one drug candidate in clinical development: resminostat.

4SC aims to generate future growth and enhance its enterprise value by entering into partnerships with pharmaceutical and biotech companies and/or the eventual marketing and sales of approved drugs in select territories by 4SC itself.

4SC is headquartered in Planegg-Martinsried near Munich, Germany. The Company had 39 employees as of 31 March 2022 and is listed on the Prime Standard of the Frankfurt Stock Exchange (FSE Prime Standard: VSC; ISIN: DE000A3E5C40).

Forward-looking information

Information set forth in this press release contains forward-looking statements, which involve risks and uncertainties. The forward-looking statements contained herein represent the judgement of 4SC as of the date of this press release. Such forward-looking statements are neither promises nor guarantees but are subject to a variety of risks and uncertainties, many of which are beyond 4SC's control, and which could cause actual results to differ materially from those contemplated in these forward-looking statements. 4SC expressly disclaims any obligation or undertaking to release any updates or revisions to any such statements to reflect any change in its expectations or any change in events, conditions or circumstances on which any such statement is based.

Contact

ir-pr@4sc.com
+49 89 700763-0

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Emitter:	4SC AG Fraunhoferstr. 22 82152 Planegg-Martinsried Germany
Contact Person:	Jason Loveridge
Phone:	+49 89 700763-0
E-Mail:	ir-pr@4sc.com
Website:	www.4sc.de
ISIN(s):	DE000A3E5C40 (Share)
Stock Exchange(s):	Regulated Market in Frankfurt; Free Market in Berlin, Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate