Biofrontera AG: Scottish Medicines Consortium (SMC) recommends Ameluz® for the treatment of basal cell carcinoma

Leverkusen (pta035/28.02.2018/14:45 UTC+1) Biofrontera AG (ISIN: DE0006046113), the specialist for the treatment of sun-induced skin cancer, has received approval for the reimbursement of Ameluz® by the Scottish Medicines Consortium SMC. The SMC recommends the prescription of Ameluz® for the treatment of superficial or nodular basal cell carcinoma (BCC) within the National Health Service (NHS). The decision of the Scottish authority, which was preceded by a similar positive recommendation in Wales, is within the UK also accepted for England as long as no separate process is carried out.

"We are pleased with SMC's decision to recommend Ameluz® for the treatment of basal cell carcinoma within the NHS. Basal cell carcinoma is the most common cancer in Britain. These patients can now benefit from photodynamic therapy in conjunction with Ameluz® as an innovative treatment method", said Prof. Dr. Hermann Lübbert, CEO of Biofrontera AG.

In its explanatory statement, the SMC points out, among other things, that non-surgical techniques are often considered for lesions with a low risk of recurrence. However, patients for whom surgical removal is unsuitable or who are at an unacceptable risk of scarring would have few effective treatment options. The SMC therefore sees Ameluz® as an excellent alternative that would reduce the need for more cost intensive treatment at a later date.

"Basal cell carcinomas are usually not life-threatening, but they can grow quickly and uncontrolled. Patients may be afraid of surgical removal of the lesions or fear the cosmetic outcome. Photodynamic therapy with Ameluz® not only provides very good efficacy combined with an excellent cosmetic result, but also the skin rejuvenation following the treatment is a welcome side effect", said Prof. Dr. Lübbert.

SMC made its decision based on the Phase III study completed by Biofrontera in 2016, in which Ameluz® was directly compared with a competitor product.

Enquiries, please contact:

Biofrontera AG
Thomas Schaffer, Chief Financial Officer
+49 (0) 214 87 63 2 0
press@biofrontera.com

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+44(0) 20 7729 0805

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IR: Tram Bui
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PR: Kirsten Thomas
+1 508-280-6592

About Biofrontera:
Biofrontera AG is an international biopharmaceutical company specializing in the development and commercialization of a platform of pharmaceutical products for the treatment of dermatological conditions and diseases caused primarily by exposure to sunlight that results in sun damage to the skin. Biofrontera's approved products focus on the treatment in the U.S. and Europe of actinic keratoses, which are skin lesions that can sometimes lead to skin cancer, as well as the treatment of certain forms of basal cell carcinoma in the European Union. American Depositary Shares representing Biofrontera's ordinary shares are listed on the NASDAQ Capital Market under the symbol "BFRA", and Biofrontera's ordinary shares are listed in the Frankfurt Stock Exchange (B8F, ISIN: DE0006046113). Information is also available at http://www.biofrontera.com .

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Emitter:	Biofrontera AG Hemmelrather Weg 201 51377 Leverkusen Germany
Contact Person:	Investor & public relations
Phone:	+49 (0) 214 87 63 20
E-Mail:	press@biofrontera.com
Website:	www.biofrontera.com
ISIN(s):	DE0006046113 (Share)
Stock Exchange(s):	Regulated Market in Dusseldorf, Frankfurt; Free Market in Berlin, Munich, Stuttgart, Tradegate